By way of example, the diversion of methadone and buprenorphine from opioid agonist treatment is claimed to generally be an important dilemma in a few nations (see Section Synthetic opioid trafficking). Furthermore, we see a craze of fall in cost from 2014 to 2019 of some opioids for example heroin, oxycodone, and fentanyl, which may cause extre

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